Fexaramine is a new diet pill that is still in the experimental stages and has not, as yet, been made available to the public.
Interest in Fexaramine as a possible aid to weight loss was fuelled in January 2015, when a number of media publications ran features on the drug and compared taking the pills to eating an imaginary meal.
However, results to an early study were first published in 2003, so Fexaramine has been in development for a long time and, unlike most other diet pills fexaramine does not dissolve into the blood.
Its actions are confined to the intestines, a fact that should, in theory, make it less likely to cause side effects.
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Who Makes Fexaramine?
Fexaramine was developed at the Salk Institute for Biological Studies (USA). The institute was founded in the early 1960s by Jonas Salk, M.D. (developer of the polio vaccine) and is currently conducting research into several major health problems including Alzheimer’s disease and AIDs.
Fexaramine Pros and Cons at a Glance
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What is Fexaramine and What Does it Do?
Speaking in techno-babble, Fexaramine is a compound that acts as an as an agonist of the farnesoid X receptor (FXR) and triggers specific changes within the body that are believed to result in weight loss. It all gets very complicated, so let’s forget the technobabble and just look at the bare facts of the matter.
Fexaramine is an anti-obesity drug that appears to have the ability to trick the body into behaving in a manner that would be consistent to its behaviour after a meal had been consumed.
According to Roland Evans (director of the Gene Expression Laboratory at the Salk Institute), whenever a meal is eaten the presence of the food in the digestive organs triggers the release of bile acids that are necessary to aid the digestion process and help the body absorb vital nutrients. When these acids are released blood flow within the digestive organs is increased ready to transport the anticipated nutrients around the body and the fat burning process is initiated. Comparing the situation to a relay race, Evans states: “Once you start the relay, the fat tissue needs to anticipate food before it’s there.”
Fexaramine Clinical Research
As yet, the weight loss potential of Fexaramine has not been tested on humans, but tests conducted on laboratory mice have produced some good results. The mice were given daily doses of the drug for five weeks and several benefits were noted by the researchers:
- Reduced blood sugar levels
- Lower cholesterol
- Converts (dangerous) white fat into (healthy) brown fat
A rise in body temperature was also noted, suggesting thermogenic fat burning.
Fexaramine Key ingredients
The key ingredient is Fexaramine—hence the name.
How to Take Fexaramine
Fexaramine is not yet available for human use, so the probable dosage is unknown.
Potential for Side Effects
It is still early days; fexaramine has never been tested on humans or released to the general public, so there is no way of knowing what the possible side effects may be. However, the Salk Institute plans to conduct further studies—including human trials—and fully assess the drug’s potentials benefits and possible side effects before bringing it to market. How long all this will take is anybody’s guess, but such a responsible attitude demands the deepest respect. Far too many manufacturers have released inadequately tested products in the past and when troubles arise it is the consumer that must pay for that mistake, often with devastating results.
Purchasing Options & Considerations
At the time of writing, fexaramine was still in the experimental stage and had not been made available to the public.
What Is Available Now
Although Fexaramine has some momentum behind it, it doesn’t really offer anything new. There are products on the market now that offer an appetite suppressing and fat burning mechanic of action.
PhenQ for example has been available to buy in many countries without prescription.